producer 不能正常生产数据到kafka集群?

存在60个java producer进程，同时生产数据到5个节点的kafka集群。一部分producer丢失数据，一部分producer完全生产不了数据，生产不了数据的producer有一下日志：

09:43:19.354 [kafka-producer-network-thread | producer-1] DEBUG o.apache.kafka.clients.NetworkClient - [Producer clientId=producer-1] Initialize connection to node vm121:9092 (id: -5 rack: null) for sending metadata request
09:43:19.354 [kafka-producer-network-thread | producer-1] DEBUG o.apache.kafka.clients.NetworkClient - [Producer clientId=producer-1] Initiating connection to node vm121:9092 (id: -5 rack: null)
09:43:19.370 [kafka-producer-network-thread | producer-1] DEBUG o.a.kafka.common.metrics.Metrics - Added sensor with name node--5.bytes-sent
09:43:19.371 [kafka-producer-network-thread | producer-1] DEBUG o.a.kafka.common.metrics.Metrics - Added sensor with name node--5.bytes-received
09:43:19.372 [kafka-producer-network-thread | producer-1] DEBUG o.a.kafka.common.metrics.Metrics - Added sensor with name node--5.latency
09:43:19.372 [kafka-producer-network-thread | producer-1] DEBUG o.a.kafka.common.network.Selector - [Producer clientId=producer-1] Created socket with SO_RCVBUF = 32768, SO_SNDBUF = 131072, SO_TIMEOUT = 0 to node -5
09:43:19.372 [kafka-producer-network-thread | producer-1] DEBUG o.apache.kafka.clients.NetworkClient - [Producer clientId=producer-1] Completed connection to node -5. Fetching API versions.
09:43:19.373 [kafka-producer-network-thread | producer-1] DEBUG o.apache.kafka.clients.NetworkClient - [Producer clientId=producer-1] Initiating API versions fetch from node -5.
09:43:49.397 [kafka-producer-network-thread | producer-1] DEBUG o.apache.kafka.clients.NetworkClient - [Producer clientId=producer-1] Disconnecting from node -5 due to request timeout.
09:43:49.397 [kafka-producer-network-thread | producer-1] DEBUG o.apache.kafka.clients.NetworkClient - [Producer clientId=producer-1] Give up sending metadata request since no node is available

这个producer所在的服务器telnet 集群每个节点的9092都是可以正常连接的，这个老师能给一点排查意见吗